Connectivity Map

Connectivity Map. World map connection Royalty Free Vector Image The second challenge in the 2016 Connectivity Map series asked competitors to speed up the existing algorithm. We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and disease states are connected by virtue of common gene-expression signatures

Data Center Network Map TulsaConnect
Data Center Network Map TulsaConnect from tc-dev.tulsaconnect.com

The second challenge in the 2016 Connectivity Map series asked competitors to speed up the existing algorithm. These are the questions the Connectivity Map project set.

Data Center Network Map TulsaConnect

Such a catalog of connections could serve as a functional look-up table of the genome; we termed this concept the Connectivity Map (CMap) The Connectivity Map is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of decisive functional connections between drugs, genes, and diseases The Research Article "The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease" (29 Sept

Data Center Network Map TulsaConnect. To date, CMap has generated a library containing over 1.5M gene expression profiles from ~5,000 small-molecule compounds, and ~3,000 genetic reagents, tested in multiple cell types Here, we report more than a 1,000-fold scale-up of the CMap as part of the NIH LINCS Consortium, made possible by a new, low-cost, high-throughput reduced representation.

Connection Map Data Viz Project. The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them These are the questions the Connectivity Map project set.